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Neurontin 300 cena for the first time in 2005 The new drug, however, also faces competition, with the FDA having approved two other new therapies for multiple sclerosis (MS), which has been difficult to treat effectively. The FDA has approved several new drugs to treat MS, but only recently have its approval times begun to catch up with the pace of drug discovery. The U.S. National Multiple Sclerosis Society said patients should buy neurontin online uk be aware that the new therapy may not work for some people, or at all. Multiple sclerosis is a chronic disease that affects nerve cells in the brain and spinal cord, is characterized by symptoms including blurred vision, muscle weakness, numbness and tingling, depression fatigue. The disease is often diagnosed in the late teens or early 20s, during the mid- to late 20s early 30s, and it is not clear why some people respond to the drug and others do not. However, most scientists and patients now believe that MS symptoms were caused by a complex interaction between multiple factors, including the immune system. "With the new therapy, most of patients who had previously experienced some relief from MS symptoms experienced complete relief," said Dr. Stephen E. D'Amelio, chairman of the neurology department at University of Texas Southwestern Medical Center in Dallas. "In our experience, it was in the early to mid stages of the disease, when some symptoms are the most severe. But by treating early, the disease is slowed in its progression, and the side effects are reduced." But the new therapy has not been accepted by the FDA. agency's Advisory Committee on Investigational Drugs (ACIP) has issued a negative statement on the new therapy, which is currently undergoing clinical trials. "The clinical trial results are disappointing, given the many promising indications for treatment of multiple sclerosis, including a high incidence of remission and a high rate of progression the disease with most severe forms," said ACIP chairman Dr. Daniel J. Leffler, of the University North Carolina in Chapel Hill. "The safety and efficacy data also appear modest and inconclusive, particularly for the most serious and disabling forms of MS. This is a matter of great concern and to the committee, given potential therapeutic benefits and Neurontin 270 pills 20 mg - 295.48$ side effects." The advisory committee noted that safety concerns were discussed in an earlier "black box" warning on the drug. That was issued in 2005 after the FDA received reports of two cases blindness and one of paralysis in patients taking cenapride. The FDA issued warning to provide more information about the risks and recommended that consumers who had taken the drug should stop. The advisory committee also said that the drug's mechanism of action is not clearly known. "It is possible that cenapride may work by blocking the breakdown of a certain type abnormal protein, which is involved in multiple sclerosis and other types of autoimmune diseases," the advisory committee said. "This mechanism is not clear and it possible that other drugs used in the treatment of multiple sclerosis may also have this effect." The committee said that while number of approved drugs for MS has grown from neurontin kapsule 300 mg cena 17 approved in 1989 to 18 2005, it is not clear the number of drugs approved for MS will continue to rise. The committee said that there is a need for evidence-based guidelines to guide the safe use of all new investigational therapies for MS. "The committee notes that there is a need for improved understanding of the underlying disease mechanisms by which these drugs exert their activity, which will help physicians to understand the risks and benefits of these therapies in the context of patients' individual specific medical histories and of other underlying disease," the committee said. However, the committee also said agency should continue to encourage trials of all new drugs (patent applications approved in the last five years) with a specific focus on MS because that is where the majority of MS patients are diagnosed and treated. "The Committee believes that the evidence supporting use of cenapride in the treatment relapsing forms of MS is largely limited to a few small, single-center studies that had some limited success," the ACIP said. D'Amelio said that even though the drug has been approved for the treatment of relapsing forms MS, it may not work for all patients and may not be able to used treat all patients who have relapsing forms of the disease because they may also be affected by other conditions. He said that cannot say whether or not cenapride works for everyone because he can only give patients the information they had before took the drug and they may be able to tell themselves if they will benefit from it. "If you take my patients out of the picture, results are not as good, because we still have to see what happens with people who take the drug, because it's not proven to"



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